Ryoichiro Kageyama, Kyoto University, Japan
Ryoichiro Kageyama received his MD in 1982 and his PhD in 1986 from Kyoto University. In 1997, he became Professor at Institute for Virus Research, Kyoto University. In 2006, he was appointed Director of the same institute (until 2010). In 2013, he was appointed Deputy Director of Institute for Integrated Cell-Material Sciences, Kyoto University. His research interest has been the elucidation of the transcription factor networks that regulate embryogenesis. He found that the basic helix-loop-helix factors Hes1 and Hes7 regulate neurogenesis and somitogenesis, respectively, under the control of Notch signaling. Furthermore, he showed that Hes1 and Hes7 expression oscillates by negative feedback, and that this oscillation is critical for tissue morphogenesis.
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